The BCDSP has published more than 400 epidemiological studies and methodological reviews in peer-reviewed medical journals covering a broad range of drugs, disease areas and outcomes. Research highlights a selection of these articles by topic. The full list of BCDSP publications can be found below.
[Historical items are still being added]
- Comparison of Epidemiological Estimates for 19 Cancer Types Using Electronic Health Record Databases in England: An Analysis of CPRD Aurum and CPRD GOLD Databases with Linked Hospital Episode Statistics and Cancer Registry DataJournal: Clinical Epidemiology Authors: Anna B Chaplin, Olia Archangelidi, Katrina Wilcox Hagberg, David Neasham, George Kafatos NLM Citation: Chaplin AB, Archangelidi O, Hagberg KW, Neasham D, Kafatos G. Comparison of Epidemiological Estimates for 19 Cancer Types Using Electronic Health Record Databases in England: An Analysis of CPRD Aurum and CPRD GOLD Databases with Linked Hospital Episode Statistics and Cancer…
- Utilization of Oral Contraceptives and Hormone Therapy for Menopause Among Female Individuals With Migraine With Aura: A Descriptive StudyJournal: Pharmacoepidemiology and Drug Safety Authors: Liza R Gibbs, Matthew P Fox, Hugo J Aparicio, Susan Jick NLM Citation: Gibbs LR, Fox MP, Aparicio HJ, Jick S. Utilization of Oral Contraceptives and Hormone Therapy for Menopause Among Female Individuals With Migraine With Aura: A Descriptive Study. Pharmacoepidemiol Drug Saf. 2025 Nov;34(11):e70266. doi: 10.1002/pds.70266. PMID: 41236401.…
- Risk of Major Congenital Anomalies in Offspring of Patients Exposed to Treatments for Bipolar Disorder During PregnancyPresented: ICPE 2025 in Washington DC, USA Authors: Catherine Vasilakis-Scaramozza, Katrina Wilcox Hagberg, Rebecca Persson, and Susan S. Jick
- Evaluating the Risk of Stroke among Female Patients using Osteoporosis Treatments (with Online Methods Appendix)Presented: ICPE 2025 in Washington DC, USA Authors: Tzu-Hsuan Yang, Rebecca Persson, Zarena Jafry, Katrina Wilcox Hagberg, Catherine Vasilakis-Scaramozza, Susan S Jick Abstract Background: Information on cardiovascular safety of osteoporosis treatments is important to help patients and clinicians choose between osteoporosis treatment options. Studies have reported increased risks of fatal stroke among users of selective…
- Osteoporosis Treatments and the Risk of Myocardial Infarction in Female Patients (with Online Methods Appendix)Presented: ICPE 2025 in Washington DC, USA Authors: Tzu-Hsuan Yang, Rebecca Persson, Zarena Jafry, Katrina Wilcox Hagberg, Catherine Vasilakis-Scaramozza, Susan S Jick Abstract Background: Information on safety of osteoporosis treatments with respect to major cardiovascular disease (CVD) outcomes, including myocardial infarction (MI), is important information for patients and clinicians choosing between treatment options. Objective: To…
- Risk of Autism or Developmental Delay in Offspring of Patients Exposed to Treatments for Bipolar Disorder During PregnancyPresented: ICPE 2025 in Washington DC, USA Authors: Catherine Vasilakis-Scaramozza, Katrina Wilcox Hagberg, Rebecca Persson, and Susan S. Jick
- Validation of Clinical Practice Research Datalink (CPRD) Aurum Mother-Baby LinkJournal: Pharmacoepidemiology and Drug Safety Authors: Catherine Vasilakis-Scaramozza, Rebecca Persson, George Kafatos, David Neasham, Katrina Wilcox Hagberg, Susan Jick NLM Citation: Vasilakis-Scaramozza C, Persson R, Kafatos G, Neasham D, Hagberg KW, Jick S. Validation of Clinical Practice Research Datalink (CPRD) Aurum Mother-Baby Link. Pharmacoepidemiol Drug Saf. 2025 Feb;34(2):e5860. doi: 10.1002/pds.5860. PMID: 39961733. Abstract Purpose: Assess the validity of the Clinical Practice…
- Treatment for osteoporosis and risk of osteonecrosis of the jaw among female patients in the United Kingdom Clinical Practice Research DatalinkJournal: Osteoporosis International Authors: Rebecca Persson, Katrina Wilcox Hagberg, Emma Pranschke, Catherine Vasilakis-Scaramozza, Susan Jick NLM Citation: Persson R, Hagberg KW, Pranschke E, Vasilakis-Scaramozza C, Jick S. Treatment for osteoporosis and risk of osteonecrosis of the jaw among female patients in the United Kingdom Clinical Practice Research Datalink. Osteoporos Int. 2025 Jan;36(1):47-60. doi: 10.1007/s00198-024-07262-7. Epub 2024 Oct 14. PMID:…
- Risk of Venous Thromboembolism in Statin Users Compared to Fibrate Users in the United Kingdom Clinical Practice Research Datalink (UK CPRD) GOLDJournal: Clinical Epidemiology Authors: Olulade Ayodele, Howard J Cabral, David D McManus, Susan S Jick NLM Citation: Ayodele O, Cabral HJ, McManus DD, Jick SS. Risk of Venous Thromboembolism in Statin Users Compared to Fibrate Users in the United Kingdom Clinical Practice Research Datalink (UK CPRD) GOLD. Clin Epidemiol. 2024 Oct 5;16:683-697. doi: 10.2147/CLEP.S481448. PMID: 39386131; PMCID: PMC11463176.…
- Staging and clean room: Constructs designed to facilitate transparency and reduce bias in comparative analyses of real-world dataJournal: Pharmacoepidemiology and Drug Safety Authors: Paul Muntner, Rohini K Hernandez, Shia T Kent, James E Browning, David T Gilbertson, Kathleen E Hurwitz, Susan S Jick, Edward C Lai, Timothy L Lash, Keri L Monda, Kenneth J Rothman, Brian D Bradbury, M Alan Brookhart NLM Citation: Muntner P, Hernandez RK, Kent ST, Browning JE, Gilbertson DT, Hurwitz KE, Jick SS, Lai EC, Lash TL, Monda KL, Rothman…
- Strategy for identifying insulin pump use in Clinical Practice Research Datalink GOLDJournal: MedRxiv – the preprint server for health sciences Authors: Rebecca Persson, Todd Sponholtz, Brenda N Baak, Susan S Jick NLM Citation: Persson R, Sponholtz T, Baak B N, Jick S S. Strategy for identifying insulin pump use in Clinical Practice Research Datalink GOLD. medRxiv 302778 [Preprint]. February 13, 2024. Available from: DOI 10.1101/2024.02.13.24302778 Abstract Background: Clinical…
- Use of the CPRD Aurum Database: Insights Gained from New Data Quality AssessmentsJournal: Clinical Epidemiology Authors: Susan Jick, Catherine Vasilakis-Scaramozza, Rebecca Persson, David Neasham, George Kafatos, Katrina Wilcox Hagberg NLM Citation: Jick S, Vasilakis-Scaramozza C, Persson R, Neasham D, Kafatos G, Hagberg KW. Use of the CPRD Aurum Database: Insights Gained from New Data Quality Assessments. Clin Epidemiol. 2023 Dec 16;15:1219-1222. doi: 10.2147/CLEP.S434832. PMID: 38126004; PMCID: PMC10732313. Abstract Ongoing evaluation of any electronic…
- Presence of Breast Cancer Information Recorded in United Kingdom Primary Care Databases: Comparison of CPRD Aurum and CPRD GOLD (Companion Paper 1)Journal: Clinical Epidemiology Authors: Katrina Wilcox Hagberg, Catherine Vasilakis-Scaramozza, Rebecca Persson, David Neasham, George Kafatos, Susan Jick NLM Citation: Hagberg KW, Vasilakis-Scaramozza C, Persson R, Neasham D, Kafatos G, Jick S. Presence of Breast Cancer Information Recorded in United Kingdom Primary Care Databases: Comparison of CPRD Aurum and CPRD GOLD (Companion Paper 1). Clin Epidemiol. 2023 Dec 16;15:1183-1192. doi: 10.2147/CLEP.S434795.…
- Correctness and Completeness of Breast Cancer Diagnoses Recorded in UK CPRD Aurum and CPRD GOLD Databases: Comparison to Hospital Episode Statistics and Cancer Registry (Companion Paper 2)Journal: Clinical Epidemiology Authors: Katrina Wilcox Hagberg, Catherine Vasilakis-Scaramozza, Rebecca Persson, David Neasham, George Kafatos, Susan Jick NLM Citation: Hagberg KW, Vasilakis-Scaramozza C, Persson R, Neasham D, Kafatos G, Jick S. Correctness and Completeness of Breast Cancer Diagnoses Recorded in UK CPRD Aurum and CPRD GOLD Databases: Comparison to Hospital Episode Statistics and Cancer Registry (Companion Paper 2). Clin Epidemiol.…
- Comparison of Rheumatoid Arthritis Information Recorded in UK CPRD Aurum and CPRD GOLD Databases (Companion Paper 3)Journal: Clinical Epidemiology Authors: Catherine Vasilakis-Scaramozza, Katrina Wilcox Hagberg, Rebecca Persson, George Kafatos, Joe Maskell, David Neasham, Susan Jick NLM Citation: Vasilakis-Scaramozza C, Hagberg KW, Persson R, Kafatos G, Maskell J, Neasham D, Jick S. Comparison of Rheumatoid Arthritis Information Recorded in UK CPRD Aurum and CPRD GOLD Databases (Companion Paper 3). Clin Epidemiol. 2023 Dec 16;15:1207-1218. doi: 10.2147/CLEP.S434831. PMID: 38126003;…
- Incomplete capture of apremilast in Clinical Practice Research Datalink Aurum: An example of exposure misclassification of specialty treatments in United Kingdom general practice databasesJournal: Pharmacoepidemiology and Drug Safety Authors: Rebecca Persson, Susan Jick NLM Citation: Persson R, Jick S. Incomplete capture of apremilast in Clinical Practice Research Datalink Aurum: An example of exposure misclassification of specialty treatments in United Kingdom general practice databases. Pharmacoepidemiol Drug Saf. 2023 Oct 2. doi: 10.1002/pds.5707. Epub ahead of print. PMID: 37786242. Abstract Purpose: Nearly…
- To Link or Not to Link: Insights from comparison of CPRD Aurum and CPRD GOLD with linked Hospital Episode Statistics (HES) APC, HES Outpatient, and Cancer Registry dataPresented: ICPE 2023 in Halifax, Nova Scotia Authors: Katrina Wilcox Hagberg, Catherine Vasilakis-Scaramozza, Rebecca Persson, George Kafatos, David E Neasham, Susan S Jick Background: Clinical Practice Research Datalink (CPRD) Aurum and GOLD are valuable sources of primary care (GP) data. Linked data adds additional information about care provided in secondary and hospital settings. The decision…
- Extent of apremilast exposure misclassification in CPRD Aurum: a validation studyPresented: ICPE 2023 in Halifax, Nova Scotia Authors: Rebecca Persson, Susan S Jick Abstract Background: United Kingdom general practice databases, including the Clinical Practice Research Datalink (CPRD), are important resources for pharmacoepidemiology and pharmacovigilance as most drugs are prescribed by general practitioners (GPs) even if initiated by a specialist. However, during the conduct of a…
- Assessing the Risk of Developing Delirium on Admission to Inpatient Rehabilitation: A Clinical Prediction ModelJournal: Journal of the American Medical Directors Association Authors: Marco G Ceppi, Marlene S Rauch, Julia Spöndlin, Christoph R Meier, Peter S Sándor NLM Citation: Ceppi MG, Rauch MS, Spöndlin J, Meier CR, Sándor PS. Assessing the Risk of Developing Delirium on Admission to Inpatient Rehabilitation: A Clinical Prediction Model. J Am Med Dir Assoc. 2023 Aug 10:S1525-8610(23)00632-1. doi:…
- Pharmacologically Treated Anxiety and Depression in People Diagnosed with von Willebrand Disease: Matched Cohort StudyJournal: Journal of Blood Medicine Authors: Katrina Wilcox Hagberg, Susan Jick, Gülden Özen, Ping Du NLM Citation: Hagberg KW, Jick S, Özen G, Du P. Pharmacologically Treated Anxiety and Depression in People Diagnosed with von Willebrand Disease: Matched Cohort Study. J Blood Med. 2023 Jul 11;14:413-425. doi: 10.2147/JBM.S407993. PMID: 37456530; PMCID: PMC10349568. Abstract Background: People diagnosed with von Willebrand…
Select from the Categories below for a compiled list of Articles associated with the Category
- 5-Alpha Reductase Inhibitor 5ARI
- Commentary
- CPRD
- Developmental Disabilities
- Disease Epidemiology Studies
- Drug Safety Studies
- Drugs and risk of cancer
- Early work examples
- Maternal and Child health
- Mental Health
- Multiple sclerosis
- Other important conditions
- Outcome and Exposure validation
- PhD Studies
- Rare and understudied diseases
- Recent student studies conducted at BCDSP
- Recent work examples
- Safety of drugs in pregnancy
- Safety of hormonal contraceptives
- Safety of new therapies for autoimmune disorders
- Safety of other hormone therapies
- Safety of other important drugs
- Select Publications
- Student Studies
- Uncategorized
- Validation Studies
- Venous Thromboembolism VTE