The BCDSP has published more than 400 epidemiological studies and methodological reviews in peer-reviewed medical journals covering a broad range of drugs, disease areas and outcomes. Research highlights a selection of these articles by topic. The full list of BCDSP publications can be found below.
[Historical items are still being added]
- Staging and clean room: Constructs designed to facilitate transparency and reduce bias in comparative analyses of real-world dataJournal: Pharmacoepidemiology and Drug Safety Authors: Paul Muntner, Rohini K Hernandez, Shia T Kent, James E Browning, David T Gilbertson, Kathleen E Hurwitz, Susan S Jick, Edward C Lai, Timothy L Lash, Keri L Monda, Kenneth J Rothman, Brian D Bradbury, M Alan Brookhart NLM Citation: Muntner P, Hernandez RK, Kent ST, Browning JE, Gilbertson DT, Hurwitz KE, Jick SS, Lai EC, Lash TL, Monda KL, Rothman…
- Strategy for identifying insulin pump use in Clinical Practice Research Datalink GOLDJournal: MedRxiv – the preprint server for health sciences Authors: Rebecca Persson, Todd Sponholtz, Brenda N Baak, Susan S Jick NLM Citation: Persson R, Sponholtz T, Baak B N, Jick S S. Strategy for identifying insulin pump use in Clinical Practice Research Datalink GOLD. medRxiv 302778 [Preprint]. February 13, 2024. Available from: DOI 10.1101/2024.02.13.24302778 Abstract Background: Clinical…
- Use of the CPRD Aurum Database: Insights Gained from New Data Quality AssessmentsJournal: Clinical Epidemiology Authors: Susan Jick, Catherine Vasilakis-Scaramozza, Rebecca Persson, David Neasham, George Kafatos, Katrina Wilcox Hagberg NLM Citation: Jick S, Vasilakis-Scaramozza C, Persson R, Neasham D, Kafatos G, Hagberg KW. Use of the CPRD Aurum Database: Insights Gained from New Data Quality Assessments. Clin Epidemiol. 2023 Dec 16;15:1219-1222. doi: 10.2147/CLEP.S434832. PMID: 38126004; PMCID: PMC10732313. Abstract Ongoing evaluation of any electronic…
- Presence of Breast Cancer Information Recorded in United Kingdom Primary Care Databases: Comparison of CPRD Aurum and CPRD GOLD (Companion Paper 1)Journal: Clinical Epidemiology Authors: Katrina Wilcox Hagberg, Catherine Vasilakis-Scaramozza, Rebecca Persson, David Neasham, George Kafatos, Susan Jick NLM Citation: Hagberg KW, Vasilakis-Scaramozza C, Persson R, Neasham D, Kafatos G, Jick S. Presence of Breast Cancer Information Recorded in United Kingdom Primary Care Databases: Comparison of CPRD Aurum and CPRD GOLD (Companion Paper 1). Clin Epidemiol. 2023 Dec 16;15:1183-1192. doi: 10.2147/CLEP.S434795.…
- Correctness and Completeness of Breast Cancer Diagnoses Recorded in UK CPRD Aurum and CPRD GOLD Databases: Comparison to Hospital Episode Statistics and Cancer Registry (Companion Paper 2)Journal: Clinical Epidemiology Authors: Katrina Wilcox Hagberg, Catherine Vasilakis-Scaramozza, Rebecca Persson, David Neasham, George Kafatos, Susan Jick NLM Citation: Hagberg KW, Vasilakis-Scaramozza C, Persson R, Neasham D, Kafatos G, Jick S. Correctness and Completeness of Breast Cancer Diagnoses Recorded in UK CPRD Aurum and CPRD GOLD Databases: Comparison to Hospital Episode Statistics and Cancer Registry (Companion Paper 2). Clin Epidemiol.…
- Comparison of Rheumatoid Arthritis Information Recorded in UK CPRD Aurum and CPRD GOLD Databases (Companion Paper 3)Journal: Clinical Epidemiology Authors: Catherine Vasilakis-Scaramozza, Katrina Wilcox Hagberg, Rebecca Persson, George Kafatos, Joe Maskell, David Neasham, Susan Jick NLM Citation: Vasilakis-Scaramozza C, Hagberg KW, Persson R, Kafatos G, Maskell J, Neasham D, Jick S. Comparison of Rheumatoid Arthritis Information Recorded in UK CPRD Aurum and CPRD GOLD Databases (Companion Paper 3). Clin Epidemiol. 2023 Dec 16;15:1207-1218. doi: 10.2147/CLEP.S434831. PMID: 38126003;…
- Incomplete capture of apremilast in Clinical Practice Research Datalink Aurum: An example of exposure misclassification of specialty treatments in United Kingdom general practice databasesJournal: Pharmacoepidemiology and Drug Safety Authors: Rebecca Persson, Susan Jick NLM Citation: Persson R, Jick S. Incomplete capture of apremilast in Clinical Practice Research Datalink Aurum: An example of exposure misclassification of specialty treatments in United Kingdom general practice databases. Pharmacoepidemiol Drug Saf. 2023 Oct 2. doi: 10.1002/pds.5707. Epub ahead of print. PMID: 37786242. Abstract Purpose: Nearly…
- To Link or Not to Link: Insights from comparison of CPRD Aurum and CPRD GOLD with linked Hospital Episode Statistics (HES) APC, HES Outpatient, and Cancer Registry dataPresented: ICPE 2023 in Halifax, Nova Scotia Authors: Katrina Wilcox Hagberg, Catherine Vasilakis-Scaramozza, Rebecca Persson, George Kafatos, David E Neasham, Susan S Jick Background: Clinical Practice Research Datalink (CPRD) Aurum and GOLD are valuable sources of primary care (GP) data. Linked data adds additional information about care provided in secondary and hospital settings. The decision…
- Extent of apremilast exposure misclassification in CPRD Aurum: a validation studyPresented: ICPE 2023 in Halifax, Nova Scotia Authors: Rebecca Persson, Susan S Jick Abstract Background: United Kingdom general practice databases, including the Clinical Practice Research Datalink (CPRD), are important resources for pharmacoepidemiology and pharmacovigilance as most drugs are prescribed by general practitioners (GPs) even if initiated by a specialist. However, during the conduct of a…
- Assessing the Risk of Developing Delirium on Admission to Inpatient Rehabilitation: A Clinical Prediction ModelJournal: Journal of the American Medical Directors Association Authors: Marco G Ceppi, Marlene S Rauch, Julia Spöndlin, Christoph R Meier, Peter S Sándor NLM Citation: Ceppi MG, Rauch MS, Spöndlin J, Meier CR, Sándor PS. Assessing the Risk of Developing Delirium on Admission to Inpatient Rehabilitation: A Clinical Prediction Model. J Am Med Dir Assoc. 2023 Aug 10:S1525-8610(23)00632-1. doi:…
- Pharmacologically Treated Anxiety and Depression in People Diagnosed with von Willebrand Disease: Matched Cohort StudyJournal: Journal of Blood Medicine Authors: Katrina Wilcox Hagberg, Susan Jick, Gülden Özen, Ping Du NLM Citation: Hagberg KW, Jick S, Özen G, Du P. Pharmacologically Treated Anxiety and Depression in People Diagnosed with von Willebrand Disease: Matched Cohort Study. J Blood Med. 2023 Jul 11;14:413-425. doi: 10.2147/JBM.S407993. PMID: 37456530; PMCID: PMC10349568. Abstract Background: People diagnosed with von Willebrand…
- Migraine and risk of hypertensive disorders of pregnancy: A population-based cohort studyJournal: Cephalagia: an international journal of headache Authors: Holly M Crowe, Amelia K Wesselink, Elizabeth E Hatch, Lauren A Wise, Susan S Jick NLM Citation: Crowe HM, Wesselink AK, Hatch EE, Wise LA, Jick SS. Migraine and risk of hypertensive disorders of pregnancy: A population-based cohort study. Cephalalgia. 2023 Apr;43(4):3331024231161746. doi: 10.1177/03331024231161746. PMID: 36935588. Abstract Background: Migraine is associated with…
- Characterization of the deterioration of diabetes control in patients with a subsequent diagnosis of pancreatic cancer: A descriptive studyJournal: Pancreatology Authors: Alexandra M Mueller, Christoph R Meier, Susan S Jick, Cornelia Schneider NLM Citation: Mueller AM, Meier CR, Jick SS, Schneider C. Characterization of the deterioration of diabetes control in patients with a subsequent diagnosis of pancreatic cancer: A descriptive study. Pancreatology. 2022 Apr;22(3):387-395. doi: 10.1016/j.pan.2022.03.012. Epub 2022 Mar 14. PMID: 35314354. Abstract Background: Deterioration of diabetes…
- Quality of rheumatoid arthritis recording in United Kingdom Clinical Practice Research Datalink AurumJournal: Pharmacoepidemiology and Drug Safety Authors: Catherine Vasilakis-Scaramozza, Katrina Wilcox Hagberg, Rebecca Persson, Eleanor Yelland, Tim Williams, Puja Myles, Susan S Jick NLM Citation: Vasilakis-Scaramozza C, Hagberg KW, Persson R, Yelland E, Williams T, Myles P, Jick SS. Quality of rheumatoid arthritis recording in United Kingdom Clinical Practice Research Datalink Aurum. Pharmacoepidemiol Drug Saf. 2023 Jan;32(1):73-77. doi: 10.1002/pds.5551. Epub 2022 Oct…
- Non-steroidal anti-inflammatory drugs and risk of myocardial infarction adjusting for use of proton pump-inhibitors in patients with no major risk factors: a nested case-control study in the UK Clinical Practice Research DatalinkJournal: European Heart Journal of Cardiovascular Pharmacotherapy Authors: Brenda N Baak, Susan S Jick NLM Citation: Baak BN, Jick SS. Non-steroidal anti-inflammatory drugs and risk of myocardial infarction adjusting for use of proton pump-inhibitors in patients with no major risk factors: a nested case-control study in the UK Clinical Practice Research Datalink. Eur Heart J Cardiovasc…
- Safety of Apremilast in Patients with Psoriasis and Psoriatic Arthritis: Findings from the UK Clinical Practice Research DatalinkJournal: Drug Safety Authors: Rebecca Persson, Myriam Cordey, Maria Paris, Susan Jick NLM Citation: Persson R, Cordey M, Paris M, Jick S. Safety of Apremilast in Patients with Psoriasis and Psoriatic Arthritis: Findings from the UK Clinical Practice Research Datalink. Drug Saf. 2022 Nov;45(11):1403-1411. doi: 10.1007/s40264-022-01235-7. Epub 2022 Sep 23. PMID: 36151359; PMCID: PMC9510500. Abstract Introduction: This real-world safety…
- β-Blockers and the Risk of Depression: A Matched Case-Control Study.Journal: Drug Safety Authors: Delia Bornand, Daphne Reinau, Susan S Jick, Christoph R Meier NLM Citation: Bornand D, Reinau D, Jick SS, Meier CR. β-Blockers and the Risk of Depression: A Matched Case-Control Study. Drug Saf. 2022 Feb;45(2):181-189. doi: 10.1007/s40264-021-01140-5. Epub 2022 Jan 19. PMID: 35044637; PMCID: PMC8857000. Abstract Introduction: Depression is a commonly cited adverse effect of β-blockers…
- Impact of von Willebrand Disease on Women’s Health Outcomes: A Matched Cohort Database StudyJournal: Journal of Women’s Health Authors: Katrina Wilcox Hagberg, Susan Jick, Ping Du, Françoise Truong Berthoz, Gülden Özen, Spiros Tzivelekis NLM Citation: Hagberg KW, Jick S, Du P, Truong Berthoz F, Özen G, Tzivelekis S. Impact of von Willebrand Disease on Women’s Health Outcomes: A Matched Cohort Database Study. J Womens Health (Larchmt). 2022 Sep;31(9):1262-1270. doi: 10.1089/jwh.2022.0082. Epub 2022 Aug…
- Asthma drugs and the risk of congenital anomaliesJournal: Pharmacotherapy Authors: Catherine Vasilakis-Scaramozza, Ann Aschengrau, Howard J Cabral, Susan S Jick NLM Citation: Vasilakis-Scaramozza C, Aschengrau A, Cabral HJ, Jick SS. Asthma drugs and the risk of congenital anomalies. Pharmacotherapy. 2013 Apr;33(4):363-8. doi: 10.1002/phar.1213. Epub 2013 Feb 28. PMID: 23450814. Abstract Study objective: To estimate the prevalence of congenital anomalies between the offspring of…
- Presence of Codes for Indication for Use in Clinical Practice Research Datalink Aurum: An Assessment of Benign Prostatic Hyperplasia TreatmentsJournal: Clinical Epidemiology Authors: Rebecca Persson, Katrina Wilcox Hagberg, Catherine Vasilakis-Scaramozza, Eleanor Yelland, Tim Williams, Puja Myles, Susan S Jick NLM Citation: Persson R, Hagberg KW, Vasilakis-Scaramozza C, Yelland E, Williams T, Myles P, Jick SS. Presence of Codes for Indication for Use in Clinical Practice Research Datalink Aurum: An Assessment of Benign Prostatic Hyperplasia Treatments. Clin Epidemiol. 2022 May 3;14:641-652.…
Select from the Categories below for a compiled list of Articles associated with the Category
- 5-Alpha Reductase Inhibitor 5ARI
- Commentary
- CPRD
- Developmental Disabilities
- Disease Epidemiology Studies
- Drug Safety Studies
- Drugs and risk of cancer
- Early work examples
- Maternal and Child health
- Mental Health
- Multiple sclerosis
- Other important conditions
- Outcome and Exposure validation
- PhD Studies
- Rare and understudied diseases
- Recent student studies conducted at BCDSP
- Recent work examples
- Safety of drugs in pregnancy
- Safety of hormonal contraceptives
- Safety of new therapies for autoimmune disorders
- Safety of other hormone therapies
- Safety of other important drugs
- Select Publications
- Student Studies
- Uncategorized
- Validation Studies
- Venous Thromboembolism VTE