Journal: British Journal of Cancer
Authors: D Reinau 1, C Surber 2, S S Jick 3, C R Meier 4
NLM Citation: Reinau D, Surber C, Jick SS, Meier CR. Epidemiology of basal cell carcinoma in the United Kingdom: incidence, lifestyle factors, and comorbidities. Br J Cancer. 2014 Jul 8;111(1):203-6. doi: 10.1038/bjc.2014.265. Epub 2014 May 29. PMID: 24874476; PMCID: PMC4090732.
Abstract
Background: Little is known about the epidemiology of basal cell carcinoma (BCC).
Methods: Using the Clinical Practice Research Datalink, we calculated annual incidence rates. In a case-control analysis, we examined lifestyle factors and comorbidities.
Results: Incidence rose significantly between 2000 and 2011. Basal cell carcinoma risk was increased in alcohol drinkers (slightly) and immunocompromised patients, but reduced in smokers and individuals with abnormal weight.
Conclusions: Basal cell carcinoma places a growing public health burden. Lifestyle factors do not play a major role in pathogenesis, but immunosuppression is important.
Figures
Figure 1 Sex-specific crude incidence rates (IRs) and age-standardised incidence rates (ASRs) of basal cell carcinoma first-time diagnoses in the United Kingdom from 2000 to 2011 (reference: European standard population, Waterhouse et al, 1976).
